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TB threat grows in Britain
By Barry Mason
26 July 2001
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Medical experts are warning about the developing threat of
tuberculosis (TB) in Britain, and especially in London.
The Annual Public Health Report 2000/2001 produced by the East
London & The City Health Authority highlights some of the
conditions that have enabled TB to take a hold. Entitled Health
in the East End, the report points out that under a third
of the cases were among people who had lived in the area for less
than five years. It showed that boroughs with high numbers of
notified TB cases, such as Newham, Tower Hamlets and Hackney,
were also those with higher than average levels of deprivation.
Homelessness is another factor. The report states that 25 percent
of homeless people in London are infected with TB, however only
around 2.5 percent show symptoms of the disease. The three boroughs
mentioned above also include high numbers of homeless people.
The incidence of HIV associated with TB is estimated at 7-8 percent
in London, but the report points out this is probably an underestimate.
From blood tests on pregnant women, Newham and Hackney have a
higher HIV incidence than the London average.
A detailed analysis of TB cases in London has shown that 50
percent of sufferers were unemployed, five percent had experienced
homelessness, over seven percent abused alcohol and seven percent
were infected with HIV.
The nature of the tuberculosis bacterium, with its waxy coating
of fatty acids and lipids (fats), means it needs persistent and
consistent antibiotic treatment. The drugs need to be taken for
a period of six to nine months. The report states, Sticking
to and completing a course of TB treatment is challenging in East
London. High population mobility, poverty, alcoholism, substance
abuse and cultural barriers make completion of a drug regimen
difficult.
Amongst the measures the report calls for are:
* An adequately resourced TB service and infrastructure, including
appropriate ratios of TB specialist nurses and support staff to
notifications.
* Specially constructed negative-pressure wards
with an artificially maintained air pressure lower than that outside
to contain the TB bacteria, which can be spread through the air.
* Effective infection control arrangements to ensure infectious
and drug-resistant cases of TB are managed appropriately.
* A research programme on the specific barriers to compliance
that affect TB patients in East London.
In July this year, London family doctors (GPs) have warned
of the dangers of a developing TB epidemic in the capital. This
is a disaster waiting to happen. It is only a matter of time until
London sees a serious out-break such as that in Leicester earlier
this year, said Dr Stewart Drage, secretary to several London
GP committees. Dr Michael Soljak, Director of Public Health for
Ealing, Hammersmith and Hounslow said that although three extra
nurses had been recruited to work with the TB cases this was not
enough to keep up with the rising levels of the disease. He said
the increased number of nurses would have been enough if
we hadnt seen the increase in cases. What we have found
is that we are barely keeping up with the disease.
In July 2000, Professor John Grange of the Centre for Infectious
Disease at University College London said London had become a
hotspot for the disease, and called for the number of specialist
TB nurses to be increased to a level of one nurse to every 50
notified cases of the disease. The Department of Health dismissed
his claim that the situation in Britain was waiting for
human disaster.
Improvements in health care and the widespread use of antibiotics
meant that TB was all but eradicated in the UK by the 1960s. In
1999, the Labour government abandoned the routine vaccination
programme for school children with the long established BCG vaccine,
but this has now been resumed in London with plans to restore
it nationwide.
Since 1987 there has been a resurgence of the disease. In 1990,
there were 1,600 cases in England and Wales. By 1999 there were
7,000 cases, with the biggest rise being amongst the 25-64 age
group. In 2000, nearly 400 people died of the disease nation-wide.
By 2001, the number of cases in Britain has risen to nearly 7,500,
of which 3,000 were in London. In London 50 new cases are currently
diagnosed each week. Commenting on the increase in TB cases in
London, Dr Heather Milburn, a chest physician at Guys and
St Thomas Hospital, said, Those of us who look after
TB patients may find were not able to cope.
Districts in East London have been particularly affected: Newham
with 108 cases per 100,000 of its population has made London tuberculosis
capital of the affluent Western world. The figures even
put it ahead of Russia, where the collapse of the public health
system has led to 91 cases per 100,000, whereas in India the figure
is 41 per 100,000.
The London Times of February 6 this year reports the
concerns of Professor Grange, who said, If you look at a
graph of what happened in New York ten years ago, and what is
happening now in London, the lines are very similar. TB is like
a forest fire-it may start small, but you never know when the
wind is going to get up and blow through the whole forest.
We have lobbied ministers, and the feedback has been
Problem what problem? adding, The upsurge
may go down. But if London goes the way of New York, some people
will be sorry that they did not nip it at birth.
An article in the January-February 2000 bulletin of the American
Centres for Disease Control posed the question, Could a
Tuberculosis Epidemic Occur in London as it did in New York?
The paper, by Andrew C Hayward of Nottingham University and Richard
J Coker of St Marys Hospital London, explained the similarities
between London and New York.
In both cities the rates of TB infection are greatest in areas
with low socio-economic conditions associated with large immigrant
populations. In New Yorks central Harlem the incidence of
the disease rose from 79 per 100,000 in 1980 to 170 per 100,00
in 1989. In London, the boroughs of Newham, Tower Hamlets and
Brent contained 77-79 cases per 100,000 at the time the paper
was published. The article added that in some parts of London
the rate had increased two to three-fold in the last 10 years.
In both cities, the increased incidence was found mainly among
young adults between 15-24 years of age. In both cities increasing
rates amongst homeless people were noted. The association with
HIV in both cities adds to the virulence of the disease.
In New York, by 1997, some 400 negative-pressure isolation
facilities had been put in place. In 1995 in London there were
only 103 such facilities.
The paper calls for London to learn the lessons of the epidemic
in New York. Urgent action is needed to strengthen TB control
in London if an epidemic like that in New York City is to be avoided.
See Also:
TB poses growing international health threat
[19 July 2001]
Tuberculosis on the rise in
the Washington DC area
[22 March 2001]
Drug-resistant tuberculosis
threatens millions
[16 May 2000]
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